Publications

Here you can find my scientific publications sorted by topic. Asterisks * mark shared first authors.

Chromosome mechanics and organization

• Nonlinear mechanics of human mitotic chromosomes
  A. Meijering*, Kata Sarlós*, C. Nielsen*, H. Witt, J. Harju, E. Kerklingh, G. Haasnoot, A. Bizard, I. Heller, C. Broedersz, Y. Liu, E. Peterman, I. Hickson, and G. Wuite , Nature, 605, 545–550, 2022.

• CENP-B-mediated DNA loops regulate activity and stability of human centromeres
  F. Chardon*, A. Japaridze*, H. Witt, L. Velikovsky, C. Chakraborty, T. Wilhelm, M. Dumont, W. Yang, C. Kikuti, S. Gangnard, A.-S. Mace, G. Wuite, C. Dekker, and D. Fachinetti, Mol. Cell, 82, 9, 1751-1767, 2022.

• The Mechanics of mitotic chromosomes
  T. Man*, H. Witt*, E. Peterman, G. Wuite, Quart. Rev. Biophys. (review article), 54, E10, 2021.

Cell mechanics and intermediate filaments

• Prestress and area compressibility of actin cortices determine the viscoelastic response of living cells
  A. Cordes, H. Witt, A. Gallemí-Pérez, B. Brückner, F. Grimm, M. Vache, T. Oswald, J. Bodenschatz, D. Flormann, F. Lautenschläger, M. Tarantola, and A. Janshoff, Phys. Rev. Lett. 125, 068101 2020.

• Adhesion of epithelial cells to PNIPAm treated surfaces for temperature-controlled cell sheet harvesting
  H. Kim, H. Witt, T. Oswald, and M. Tarantola, ACS Appl. Mater. Interfaces 12, 30, 33516–33529 2020.

• Lateral subunit coupling determines intermediate filament mechanics
  C. Lorenz, J. Forsting, A. V. Schepers, J. Kraxner, S. Bauch, H. Witt, S. Klumpp, and S. Köster, Phys. Rev. Lett. 123, 188102, 2019.

• Vimentin intermediate filaments undergo irreversible conformational changes during cyclic loading
  J. Forsting*, J. Kraxner*, H. Witt*, A. Janshoff, and S. Köster, Nano Lett. 19, 7349-7356, 2019.

• Adhesion strategies of Dictyostelium discoideum - a force spectroscopy study
  N. Kamprad, H. Witt, M. Schröder, C. T. Kreis, O. Bäumchen, A. Janshoff, and M. Tarantola, Nanoscale 10, 22504-22519, 2018.

• Viscoelastic properties of vimentin originate From nonequilibrium conformational changes
  J. Block*, H. Witt*, A. Candelli, J. Cabanas Danes, E. J. G. Peterman, G. J. L. Wuite, A. Janshoff, and S. Köster, Sci. Adv. 4, eaat1161, 2018.

• Nonlinear loading-rate-dependent force response of individual vimentin intermediate filaments to applied strain
  J. Block, H. Witt, A. Candelli, E. J. G. Peterman, G. J. L. Wuite, A. Janshoff, and S. Köster, Phys. Rev. Lett. 118, 048101, 2017.

Lipid bilayers

• Membrane fusion studied by colloidal probes
  H. Witt*, F. Savić*, S. Verbeek, J. Dietz, G. Tarantola, M. Oelkers, B. Geil, and A. Janshoff, Eur. Biophys. J. (review article) 50, 223–237, 2021.

• Precipitation of calcium carbonate inside giant inilamellar vesicles composed of fluid-phase lipids
  H. Witt, N. Yandrapalli, M. Sari, L. Turco, T. Robinson, and C. Steinem, Langmuir 36, 44, 13244–13250 2020.

• Detachment of giant liposomes – coupling of receptor mobility and membrane shape
  H. Witt*, M. Vache*, A. Cordes, and A. Janshoff, Soft Matter 16, 6424, 2020.

• Using force spectroscopy to probe coiled-coil assembly and membrane fusion
  H. Witt and A. Janshoff, SNAREs: Methods and Protocols, Methods in Molecular Biology (Book chapter), vol. 1860, 145-159, 2019.

• The nonbilayer lipid MGDG and the major light-harvesting complex (LHCII) promote membrane stacking in supported lipid bilayers
  D. Seiwert, H. Witt, S. Ritz, A. Janshoff, and H. Paulsen, Biochemistry 57, 2278-2288, 2018.

• The non-bilayer lipid MGDG stabilizes the major light-harvesting complex (LHCII) against unfolding
  D. Seiwert*, H. Witt*, A. Janshoff, and H. Paulsen, Sci. Rep. 7, 5158, 2017.

• SNARE-mediated membrane fusion trajectories derived from force-clamp experiments
  M. Oelkers*, H. Witt*, P. Halder, R. Jahn, and A. Janshoff, Proc. Natl. Acad. Sci. USA 110, 1582–1592, 2016.

• Size, kinetics, and free energy of clusters formed by ultraweak carbohydrate-carbohydrate bonds
  H. Witt, F. Savic, M. Oelkers, S. I. Awan, D. B. Werz, B. Geil, and A. Janshoff, Biophys. J. 110, 1582–1592, 2016.

Completely unrelated

• A versatile dinucleating ligand containing sulfonamide groups
  J. Sundberg, H. Witt, L. Cameron, M. Håkansson, J. Bendix, and C. J. McKenzie, Inorg. Chem. 53, 2873-2882, 2014.